Hi Carol,
The setting for 'Default print to file path' on the Report Options tab of User Preferences actually refers to where reports are saved when they are printed to File, such as Word or Excel, and has no effect on using Adagio ePrint for printing to PDF, and nor does Adagio ePrint have any effect on what you can do with this path. These settings are saved in the 'Common Files' in the data directory (those data files starting with the 'SD' prefix).
What happens when you try to browse for a different 'Default print to file path' from User Preferences and save the changes? An error message - if so, what is it? Does this problem happen for all users accessing these two companies or just some? Each user has their own settings saved in the 'Common Files', and of course need to be able to have write rights.
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Regards,
Softrak Tech Support