Hello CRR:
Your most recent posting seems to match what Andrew described. In that case, it is a problem in POA.
It arises with i) a new item that ii) has not been assigned to a Location yet. In IC or OE, you don't have to worry about the "assigning" step because the application does it behind the scene when you enter your first transaction against that item. POA tries to do it too but doesn't get it right.
To prevent the problem in POA, you can run a process AFTER adding new Items in IC. Do the following:
-In IC, go to Edit then Locations
-Highlight your main Location and click on Edit
-Go to the Items tab
-If you search for your new Item(s), you will see that the "Selected" column is blank
-You can assign it to your main Location by clicking on "Add"
-Or if there are many new Items, you can click on the "All Items" button
-This will link ALL Items to this Location so be certain this is what you want to do.
-Click on "Ok" to save your changes
Once you have done this, POA won't try to activate a Location when you order a new Item. Remember that the process needs to be run after any new Items are added.