Well according to our compatibility chart and the Adagio OrderEntry release notes, only versions 6.1B and 6.5A of Accpac Plus IC is compatible with Adagio OE. I suppose that would be one issue to look out for...

There is a difference in data structure for the item records and some other files, between IC 6.0x and 6.1B or 6.5A, so there is a very good chance that if you tried this out the end result would be error messages and incompatibility.