Tony:
It's a double edge sword. The speed improvement can be substantal. The risk is even bigger. The client gets all of the benefit and the dealer gets all of the risk.
I will only implement OpLocks = On if my client has all Windows 7 Pro (or better) workstations and Windows 2008R2 server. No peer to peer and no older equipment connected to the network allowed (even if not used for Adagio).
This policy is purely based upon my experience with my large client base. Sometimes OpLocks will work in a lesser environment but I've been burned by this often enough that I can no longer afford the risk.